Waikato District Blood Resource

Immunoglobulin Products - Quick Guide

Products

NZBS provides human immunoglobulin concentrate of IgG antibodies prepared from pooled plasma donations in three formulations:

for intravenous use
for subcutaneous use
for intramuscular use

Australian NBA IVIG Guideline

NHS Guidelines (2021)

English NHS IVIG Guideline

Intravenous products

There are several different intravenous products available in New Zealand. The different products have different rates for administration. Please check you have the correct infusion rate for the specific IVIg product you are administering.

PrivigenNZ
a 10% solution prepared from New Zealand donor plasma and manufactured by the same company that made IntragamP, CSL Behring. ProvigenNZ is being rolled out nationally and replaces IntragamP.
Privigen
a 10% solution manufactured in exactly the same way and the same plant as as PrivigenNZ but from European and American donor plasma. New Zealand is approximately 90% self-sufficient as a country for IVIG. For the remainder, we have Privigen.
Gamunex
a 10% IVIG solution manufactured by Grifols. This is only for patients who cannot tolerate Privigen or PrivigenNZ. We have a small stock of Gamunex. This is available only after discussion with a New Zealand Transfusion Medicine Specialist.

Subcutaneous products

There is one subcutaneous products available in New Zealand.

Hizentra
a 20% solution, is prepared from European and American donor plasma by the same manufacturer as Privigen NZ, CSL Behring. Please check administration instructions before use.

Intramuscular product

There is currently one non-specific intramuscular product in New Zealand. This is usually used for prophylaxis for hepatitis A, measles, and some other virusses.

GamaSTAN-SD
prepared from North American and European donors.

Hyperimmune products

Hyperimmune immunoglobulins are also pooled immunoglobulin concentrates but with a known level of activity against a named virus or protein. Hyperimmune immunoglobulins prepared from New Zealand donors' plasma are Anti-D, Hepatitis B Immunoglobulin, Tetanus Immunoglobulin and Zoster Immunoglobulin. Other hyperimmune immunoglobulins are available as Section 29 products.

Datasheets

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